At first blush this “Robot Chicken” segment seems to be about 14 kinds of wrong, but it’s actually a fair spoof of “Punky Brewster”, a popular TV show from the late 80s, and a cartoon spin-off that followed it. “Punky Brewster” was about a precocious young girl with no parents who dressed in outrageously colored outfits and lived in an apartment with an elderly gay man. It had lots of “very special episodes”, if you know what I mean, that addressed various, tedious social problems like homelessness, getting old, and that (contrary to what Hollywood writers were taught in Jewish day school) menstruation is actually just fine.
It’s hard to believe, but there really was an episode where Punky declared that her boobs were growing. Also, the actress who played the character, Soleil Moon Frye, did in fact suffer from gigantomastia or virginal breast hypertrophy, beginning around the time the show went off the air. By her mid-teens the preposterously large-breasted Frye was mockingly referred to as “Punky Boobster” by other kids in her high school. Soleil Moon Frye subsequently had a drastic reduction. She has only occasionally been cast in TV and movie roles in the years since, so maybe she should have gone for “moderate” instead of “drastic”.